5-isoquinolinecarboxylic acid

5-isoquinolinecarboxylic acid - Names and Identifiers

Name	Isoquinoline-5-carboxylic acid
Synonyms	ine-5-carboxyL RARECHEM AL BE 1523 5-Carboxyisoquinoline 5-Isoquinolinecarboxylicaci 5-Isoquinolinecarboxylic acid 5-isoquinolinecarboxylic acid Isoquinoline-5-carboxylic acid ISOQUINOLINE-5-CARBOXYLIC ACID 5-Carboxyisoquinoline, 2-Azanaphthalene-5-carboxylic acid
CAS	27810-64-6
EINECS	640-129-5
InChI	InChI=1/C10H7NO2/c12-10(13)9-3-1-2-7-6-11-5-4-8(7)9/h1-6H,(H,12,13)

5-isoquinolinecarboxylic acid - Physico-chemical Properties

Molecular Formula	C10H7NO2
Molar Mass	173.17
Density	1.339±0.06 g/cm3(Predicted)
Melting Point	278-281°C
Boling Point	60-62°C 11mm
Flash Point	60-62°C/11mm
Vapor Presure	2.64E-07mmHg at 25°C
BRN	129180
pKa	1.21±0.10(Predicted)
Storage Condition	2-8°C(protect from light)
Refractive Index	1.684
MDL	MFCD03788744

5-isoquinolinecarboxylic acid - Risk and Safety

Hazard Symbols	Xn - Harmful
Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R36 - Irritating to the eyes R22 - Harmful if swallowed
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S22 - Do not breathe dust.
WGK Germany	3

5-isoquinolinecarboxylic acid - Introduction

Isoquinoline-5-carboxylic acid is an organic compound with the chemical formula C10H7NO2. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
Isoquinoline-5-carboxylic acid is a white to pale yellow solid with a bitter taste. It is soluble in acid and alkaline aqueous solutions, slightly soluble in water and most organic solvents. It can be decomposed at high temperature.

Use:
Isoquinoline-5-carboxylic acid has important applications in the field of medicine. It is an important intermediate compound, often used in the synthesis of some biologically active compounds, such as drugs, pesticides and dyes. In addition, it can also be used as organic Synthesis Reagents and research compounds.

Method:
Isoquinoline-5-carboxylic acid can be prepared by a variety of methods. One of the common methods is obtained by oxidation of isoquinoline. In the specific operation, isoquinoline can be reacted with potassium permanganate (KMnO4) or hydrogen peroxide (H2O2), and finally heated to obtain Isoquinoline-5-carboxylic acid.

Safety Information:
Isoquinoline-5-carboxylic acid is generally considered to be relatively safe under normal operating conditions. However, the following matters still need to be noted:
1. Avoid contact with skin and eyes. If there is contact, rinse immediately with plenty of water.
2. During operation, avoid inhaling dust or vapor Isoquinoline-5-carboxylic acid, and maintain a well-ventilated laboratory environment.
3. Avoid contact with flammable substances and oxidants during use and storage.
4. In case of overdose or accidental exposure, seek medical attention immediately.

In general, with proper handling and storage methods, Isoquinoline-5-carboxylic acid is a relatively safe compound. However, it is still necessary to strictly abide by the safety operation procedures to ensure personal safety and laboratory safety.

Last Update：2024-04-09 20:52:54